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Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.
DOWNLOAD NOWQuercetin 3-O-α-L-arabinopyranoside is a phenol that has been found in Byrsonima crassa and has antioxidant activity.1,2 It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (IC50 = 48.6 µM).1 Quercetin 3-O-α-L-arabinopyranoside inhibits H. pylori-induced oxidative burst of isolated rat polymorphonuclear (PMN) neutrophils (IC50 = 75.3 µM).2 It reduces N-retinylidene-N-retinylethanolamine- and blue light-induced death of ARPE-19 retinal epithelial cells in a concentration-dependent manner.3 In vivo, quercetin 3-O-α-L-arabinopyranoside (25, 50, and 200 mg/kg) prevents blue light-induced retinal degeneration in a mouse model of macular degeneration.
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1. Phenolic compounds from the flowers of Nepalese medicinal plant Aconogonon molle and their DPPH free radical-
2. Effect of Byrsonima crassa and phenolic constituents on Helicobacter pylori-
3. Quercetin-