A metabolite of loratadine
Related Products
Parent Compound(s)
15625Loratadine
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Loratadine N-oxide

Item No. 35244

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-(8-chloro-5,6-dihydro-1-oxido-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid, ethyl ester
CAS Number
165739-62-8
Synonyms
  • SCH 38554
Molecular Formula
C22H23ClN2O3
Formula Weight
398.9
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: slightly solubleMethanol: slightly soluble
λmax
259 nm
SMILES
O=C(N1CC/C(CC1)=C2C3=C(CCC4=CC=C[N+]([O-])=C4\2)C=C(Cl)C=C3)OCC
InChi Code
InChI=1S/C22H23ClN2O3/c1-2-28-22(26)24-12-9-15(10-13-24)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-25(27)21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3
InChi Key
AEYRDESTWAYZTA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Loratadine N-oxide is a metabolite of the histamine H1 receptor inverse agonist loratadine (Item No. 15625).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Habicht, S.C., Duan, P., Vinueza, N.R., et al. Liquid chromatography/tandem mass spectrometry utilizing ion-molecule reactions and collision-activated dissociation for the identification of N-oxide drug metabolites. J. Pharm. Biomed. Anal. 51(4), 805-811 (2010).