A bacterial metabolite with antibacterial and fungicidal activity
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Blasticidin S

Item No. 35252

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[[(3S)-3-amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-β-D-erythro-hex-2-enopyranuronic acid
CAS Number
2079-00-7
Molecular Formula
C17H26N8O5
Formula Weight
422.4
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: solubleDMSO: solubleEthanol: solubleMethanol: solubleWater: soluble
SMILES
N=C(N)N(CC[C@H](N)CC(N[C@H]1C=C[C@H](N2C=CC(N)=NC2=O)O[C@@H]1C(O)=O)=O)C
InChi Code
InChI=1S/C17H26N8O5/c1-24(16(20)21)6-4-9(18)8-12(26)22-10-2-3-13(30-14(10)15(27)28)25-7-5-11(19)23-17(25)29/h2-3,5,7,9-10,13-14H,4,6,8,18H2,1H3,(H3,20,21)(H,22,26)(H,27,28)(H2,19,23,29)/t9-,10-,13+,14-/m0/s1
InChi Key
CXNPLSGKWMLZPZ-ZNIXKSQXSA-N
Origin
Bacterium/Streptomyces sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Blasticidin S is a bacterial metabolite originally isolated from S. griseochromogenes that has antibacterial and fungicidal activities.1 It is active against B. subtilis, S. lutea, E. coli, P. fluorescens, and M. tuberculosis, as well as the plant pathogenic fungi P. oryzae, S. mali, G. kaki, and G. lacticolor in a broth dilution assay when used at concentrations ranging from 5 to 50 µg/ml.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Takeuchi, S., Hirayama, K., Ueda, K., et al. Blasticidin S, a new antibiotic. J. Antibiot. (Tokyo) 11(1), 1-5 (1958).