A CysLT1 receptor antagonist
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CAY10788

Item No. 35324

Technical Information
Formal Name
3-(2-quinolinylmethoxy)-benzoic acid, methyl ester
CAS Number
119515-00-3
Molecular Formula
C18H15NO3
Formula Weight
Purity
≥95%
Formulation
A crystalline solid
DMF: insolDMSO: 1 mg/mlEthanol: 1 mg/mlPBS (pH 7.2): insol
λmax
229 nm
SMILES
O=C(OC)C1=CC(OCC2=NC3=CC=CC=C3C=C2)=CC=C1
InChi Code
InChI=1S/C18H15NO3/c1-21-18(20)14-6-4-7-16(11-14)22-12-15-10-9-13-5-2-3-8-17(13)19-15/h2-11H,12H2,1H3
InChi Key
INKCQRGAPBDVIZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    CAY10788 is an antagonist of the cysteinyl leukotriene 1 (CysLT1) receptor (IC50 = 3.9 µM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fiorillo, B., Sepe, V., Conflitti, P., et alStructural basis for developing multitarget compounds acting on cysteinyl leukotriene receptor 1 and G-protein-coupled bile acid receptor 1. J. Med. Chem. 64(22), 16512-16529 (2021).