A CysLT1 receptor antagonist
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CAY10789

Item No. 35325

Technical Information
Formal Name
3-(2-quinolinylmethoxy)-benzenemethanol
CAS Number
123226-28-8
Synonyms
  • [3-(Quinolin-2-ylmethoxy)phenyl]methanol
Molecular Formula
C17H15NO2
Formula Weight
Purity
≥98%
Formulation
A solid
DMF: 11 mg/mlDMSO: 5 mg/mlEthanol: 11 mg/mlPBS (pH 7.2): 0.14 mg/ml
λmax
230 nm
SMILES
OCC1=CC(OCC(C=C2)=NC3=C2C=CC=C3)=CC=C1
InChi Code
InChI=1S/C17H15NO2/c19-11-13-4-3-6-16(10-13)20-12-15-9-8-14-5-1-2-7-17(14)18-15/h1-10,19H,11-12H2
InChi Key
FARMNDXIOAHJMF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    CAY10789 is an antagonist of the cysteinyl leukotriene 1 (CysLT1) receptor (IC50 = 2.1 µM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fiorillo, B., Sepe, V., Conflitti, P., et alStructural basis for developing multitarget compounds acting on cysteinyl leukotriene receptor 1 and G-protein-coupled bile acid receptor 1. J. Med. Chem. 64(22), 16512-16529 (2021).