A CysLT1 receptor antagonist and GPBAR1 agonist
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

CAY10790

Item No. 35326

Product Insert (PDF)
Technical Information
Formal Name
3-(2-quinolinylmethoxy)-benzoic acid
CAS Number
107813-86-5
Molecular Formula
C17H13NO3
Formula Weight
279.3
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 3 mg/mlDMSO: 1 mg/ml
SMILES
OC(C1=CC(OCC(C=C2)=NC3=C2C=CC=C3)=CC=C1)=O
InChi Code
InChI=1S/C17H13NO3/c19-17(20)13-5-3-6-15(10-13)21-11-14-9-8-12-4-1-2-7-16(12)18-14/h1-10H,11H2,(H,19,20)
InChi Key
IJTITQLHFRUEQF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $49

    Add

    5 mg

    $206

    Add

    10 mg

    $339

    Add

    25 mg

    $723

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    CAY10790 is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50 = 2.8 µM) and G protein-coupled bile acid receptor 1 (GPBAR1) agonist.1 It induces receptor transactivation in HEK293T cells expressing human GPBAR1 (EC50 = 3 µM). CAY10790 (10 µM) reduces TNF-α and IL-1β levels in LPS-stimulated RAW 264.7 cells. It also reduces the proliferation of RAW 264.7 cells induced by leukotriene D4 (LTD4; Item No. 20310).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fiorillo, B., Sepe, V., Conflitti, P., et al. Structural basis for developing multitarget compounds acting on cysteinyl leukotriene receptor 1 and G-protein-coupled bile acid receptor 1. J. Med. Chem. 64(22), 16512-16529 (2021).