A carbamate fungicide
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Active Metabolite(s)
23852Carbendazim
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Thiophanate-methyl

Item No. 35402

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N,N′-[1,2-phenylenebis(iminocarbonothioyl)]bis-carbamic acid, C,C′-dimethyl ester
CAS Number
23564-05-8
Synonyms
  • NSC 170811
  • Thiophanate M
  • TM
Molecular Formula
C12H14N4O4S2
Formula Weight
342.4
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/ml
λmax
270 nm
SMILES
O=C(NC(NC1=C(NC(NC(OC)=O)=S)C=CC=C1)=S)OC
InChi Code
InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22)
InChi Key
QGHREAKMXXNCOA-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 mg

    $29

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    Product Description

    Thiophanate-methyl is a carbamate fungicide.1 It is active against a variety of fungi, including T. terrestre and G. roseum (EC50s = <1 to 1-10 µM). Thiophanate-methyl induces hepatotoxicity and increases hepatic reactive oxygen species (ROS) levels in zebrafish larvae and adults when used at concentrations of 12.5 and 25 mg/L.2 Formulations containing thiophanate-methyl have been used in the control and prevention of fungi in agriculture and landscaping.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bollen, G.J. A comparison of the in vitro antifungal spectra of thiophanates and benomyl. Neth. J. Pl. Path. 78, 55-64 (1972).

    2. Jia, K., Cheng, B., Huang, L., et al. Thiophanate-methyl induces severe hepatotoxicity in zebrafish. Chemosphere 248, 125941 (2020).