A broad-spectrum antibiotic
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Fosfomycin (calcium salt)

Item No. 35535

Technical Information
Formal Name
P-[(2R,3S)-3-methyl-2-oxiranyl]-phosphonic acid, monocalcium salt
CAS Number
26016-98-8
Synonyms
  • Phosphomycin Calcium
Molecular Formula
C3H5O4P • Ca
Formula Weight
Purity
≥95%
A solid
Water: Soluble
SMILES
O=P([O-])([C@@H]1[C@@H](O1)C)[O-].[Ca+2]
InChi Code
InChI=1S/C3H7O4P.Ca/c1-2-3(7-2)8(4,5)6;/h2-3H,1H3,(H2,4,5,6);/q;+2/p-2/t2-,3+;/m0./s1
InChi Key
YMZJBJPWTXJQMR-LJUKVTEVSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Fosfomycin is a broad-spectrum bactericidal antibiotic.1,2 It is active against Salmonella and P. aeruginosa at 1.56 and 6.25 µg/ml, respectively, as well as methicillin-sensitive S. aureus (MSSA), cephalosporin- and penicillin-resistant S. pneumoniae, methicillin-resistant S. aureus (MRSA), and vancomycin-resistant Enterococcus. Formulations containing fosfomycin have been used in the treatment of urinary tract infections.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Goto, S. Fosfomycin, antimicrobial activity in vitro and in vivo. Chemotherapy 23(Suppl. 1), 63-74 (1977).

    2. Michalopoulos, A.S., Livaditis, I.G., and Gougoutas, V. The revival of fosfomycin. Int. J. Infect. Dis. 15(11), e732-e739 (2011).