A benzyolated derivative of cytidine
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N4-benzoyl-Cytidine

Item No. 35698

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-benzoyl-cytidine
CAS Number
13089-48-0
Synonyms
  • NSC 242979
Molecular Formula
C16H17N3O6
Formula Weight
347.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble
SMILES
O[C@H]1[C@H](N2C(N=C(C=C2)NC(C3=CC=CC=C3)=O)=O)O[C@@H]([C@H]1O)CO
InChi Code
InChI=1S/C16H17N3O6/c20-8-10-12(21)13(22)15(25-10)19-7-6-11(18-16(19)24)17-14(23)9-4-2-1-3-5-9/h1-7,10,12-13,15,20-22H,8H2,(H,17,18,23,24)/t10-,12-,13-,15-/m1/s1
InChi Key
BNXBRFDWSPXODM-BPGGGUHBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 g

    $53

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    50 g

    $101

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    100 g

    $191

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    250 g

    $423

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    Product Description

    N4-benzoyl-Cytidine is a benzyolated derivative of the pyrimidine nucleoside cytidine (Item No. 29602).1 It is a substrate of uridine-cytidine kinase 1 (UCK1) and UCK2. N4-benzoyl-Cytidine also has been used in the synthesis of 2ʹ-OH protecting groups for solid-phase RNA synthesis, as well as synthetic oligonucleotides for UV light-induced and targeted gene silencing in zebrafish embryos.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Van Rompay, A.R., Norda, A., Lindén, K., et al. Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases. Mol. Pharmacol. 59(5), 1181-1186 (2001).

    2. Semenyuk, A., Földesi, A., Johansson, T., et al. Synthesis of RNA Using 2‘-O-DTM Protection. J. Am. Chem. Soc. 128(38), 12356-12357 (2006).

    3. Shestopalov, I.A., Sinha, S., and Chen, J.K. Light-controlled gene silencing in zebrafish embryos. Nat. Chem. Biol. 3(10), 650-651 (2007).