A pyrimidine nucleoside
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Labeled Version(s)
36320Cytidine-d2
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Cytidine

Item No. 29602

Technical Information
CAS Number
65-46-3
Synonyms
  • β-D-Cytidine
  • NSC 20258
Molecular Formula
C9H13N3O5
Formula Weight
Purity
≥98%
A solid
DMF: 3 mg/mlDMSO: 10 mg/mlEthanol: Slightly solublePBS (pH 7.2): 10 mg/ml
λmax
271 nm
SMILES
NC(C=CN1[C@]2([H])O[C@H](CO)[C@@H](O)[C@H]2O)=NC1=O
InChi Code
InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1
InChi Key
UHDGCWIWMRVCDJ-XVFCMESISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    Product Description

    Cytidine is a pyrimidine nucleoside composed of ribose and a cytosine base.1 It forms complementary base pairs with the purine nucleoside guanosine (Item No. 27702) in DNA and RNA. Cytidine is a precursor of uridine (Item No. 20300) and can also be phosphorylated by uridine-cytidine kinase to form CMP (Item No. 35116).2,1 It rescues inhibition of proliferation induced by knockdown of CTP synthase 1 in T cells when used at a concentration of 200 µM.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Berg, J.M., Tymoczko, J.L., and Stryer, L. Nucleotide biosynthesis. Biochemistry (2002).

    2. Chabner, B.A., Johns, D.G., Coleman, C.N., et alPurification and properties of cytidine deaminase from normal and leukemic granulocytes. J. Clin. Invest. 53(3), 922-931 (1974).

    3. Martin, E., Palmic, N., Sanquer, S., et alCTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation. Nature 510(7504), 288-292 (2014).