A monosaccharide
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D-Arabinose

Item No. 35700

Technical Information
CAS Number
10323-20-3
Synonyms
  • D-(–)-Arabinose
Molecular Formula
C5H10O5
Formula Weight
Purity
≥95%
A solid
Water: 30 mg/ml
SMILES
OC[C@@H](O)[C@@H](O)[C@H](O)C=O
InChi Code
InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4-,5+/m1/s1
InChi Key
PYMYPHUHKUWMLA-WDCZJNDASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    D-Arabinose is a monosaccharide. It has been found in the O-specific polysaccharide of LPS in P. maltophilia.1 D-Arabinose (50 and 100 mM) inhibits S. oralis, F. nucleatum, and P. gingivalis biofilm formation as well as the activity of autoinducer 2, a quorum-sensing molecule involved in the pathogenesis of periodontitis, in V. harveyi in a reporter assay.2 It reduces the growth of C. elegans (IC50 = 7.5 mM), an effect that can be reversed by D-ribose or D-fructose, but not D-glucose.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wilkinson, S.G., Galbraith, L., and Anderton, W.J. Lipopolysaccharides from Pseudomonas maltophilia: Composition of the lipopolysaccharide and structure of the side-chain polysaccharide from strain N.C.I.B. 9204. Carbohydr. Res. 112(2), 241-252 (1983).

    2. An, S.-J., Namkung, J.-U., Ha, K.-W., et alInhibitory effect of ᴅ-arabinose on oral bacteria biofilm formation on titanium discs. Anaerobe 102533 (2022).

    3. Sakoguchi, H., Yoshihara, A., Shintani, T., et alGrowth inhibitory effect of ᴅ-arabinose against the nematode Caenorhabditis elegans: Discovery of a novel bioactive monosaccharide. Bioorg. Med. Chem. Lett. 26(3), 726-729 (2106).