A metabolite of sertraline
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(1R,4R)-N-desmethyl Sertraline (hydrochloride)

Item No. 35741

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(1R,4R)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine, monohydrochloride
CAS Number
675126-09-7
Synonyms
  • (1R,4R)-N-demethyl Sertraline
Molecular Formula
C16H15Cl2N • HCl
Formula Weight
328.7
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly solubleMethanol: Slightly soluble
SMILES
N[C@@H]1CC[C@H](C2=CC(Cl)=C(C=C2)Cl)C3=C1C=CC=C3.Cl
InChi Code
InChI=1S/C16H15Cl2N.ClH/c17-14-7-5-10(9-15(14)18)11-6-8-16(19)13-4-2-1-3-12(11)13;/h1-5,7,9,11,16H,6,8,19H2;1H/t11-,16-;/m1./s1
InChi Key
YKXHIERZIRLOLD-INXKOZGQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $256

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    Product Description

    (1R,4R)-N-desmethyl Sertraline is a metabolite of the selective serotonin reuptake inhibitor (SSRI) sertraline (Item No. 14839).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Obach, R.S., Cox, L.M., and Tremaine, L.M. Sertraline is metabolized by multiple cytochrome P450 enzymes, monoamine oxidases, and glucuronyl transferases in human: An in vitro study. Drug Metab. Dispos. 33(2), 262-270 (2005).