A sesquiterpene with antiviral and anticancer activities
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(−)-β-Sesquiphellandrene

Item No. 35749

Technical Information
Formal Name
3R-[(1S)-1,5-dimethyl-4-hexen-1-yl]-6-methylene-cyclohexene
CAS Number
20307-83-9
Molecular Formula
C15H24
Formula Weight
Purity
≥95%
A neat oil
Chloroform: slightly
SMILES
C/C(C)=C\CC[C@@H]([C@@]1([H])CCC(C=C1)=C)C
InChi Code
InChI=1S/C15H24/c1-12(2)6-5-7-14(4)15-10-8-13(3)9-11-15/h6,8,10,14-15H,3,5,7,9,11H2,1-2,4H3/t14-,15+/m0/s1
InChi Key
PHWISBHSBNDZDX-LSDHHAIUSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    (–)-β-Sesquiphellandrene is a sesquiterpene that has been found in Z. officinale and has antiviral and anticancer activities.1,2 It reduces rhinovirus IB virus replication in a plaque reduction assay (IC50 = 0.44 µM).1 (–)-β-Sesquiphellandrene is cytotoxic to HCT116 cells when used at a concentration of 10 µM.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Denyer, C.V., Jackson, P., and Loakes, D.M. Isolation of antirhinoviral sesquiterpenes from ginger (Zingiber officinale). J. Nat. Prod. 57(5), 658-662 (1994).

    2. Agnihotri, V.K., ElSohly, H.N., Khan, S.I., et alConstituents of Nelumbo nucifera leaves and their antimalarial and antifungal activity. Phytochem. Lett. 1(2), 89-93 (2008).