A sesquiterpene with antiviral and neuroprotective activities
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

β-Bisabolene

Item No. 43567

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(4S)-1-methyl-4-(5-methyl-1-methylene-4-hexen-1-yl)-cyclohexene
CAS Number
495-61-4
Synonyms
  • (–)-β-Bisabolene
  • (S)-β-Bisabolene
Molecular Formula
C15H24
Formula Weight
204.4
Purity
≥85%
Formulation (Request formulation change)
A neat oil
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly soluble: 0.1-1 mg/ml
SMILES
CC1=CC[C@@H](C(CC/C=C(C)/C)=C)CC1
InChi Code
InChI=1S/C15H24/c1-12(2)6-5-7-14(4)15-10-8-13(3)9-11-15/h6,8,15H,4-5,7,9-11H2,1-3H3/t15-/m1/s1
InChi Key
XZRVRYFILCSYSP-OAHLLOKOSA-N
Origin
Plant/Mandarin oil
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    25 mg

    $35

    Add

    50 mg

    $67

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    β-Bisabolene is a sesquiterpene that has been found in Z. officinale and has antiviral and neuroprotective activities.1,2 It reduces rhinovirus IB virus replication in a plaque reduction assay (IC50 = 14.3 µg/plate).1 β-Bisabolene (31.25-125 µg/ml) protects against decreases in viability, reduces production of reactive oxygen species (ROS), and decreases levels of COX-2, nitric oxide (NO), TNF-α, and IL-1β in HMC3 human microglial cells in an in vitro model of ischemia induced by glucose-oxygen deprivation.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Denyer, C.V., Jackson, P., and Loakes, D.M. Isolation of antirhinoviral sesquiterpenes from ginger (Zingiber officinale). J. Nat. Prod. 57(5), 658-662 (1994).

    2. Zhang, X., Gao, L., Wang, J., et al. Study of the ameliorative effect of β-Bisabolene on ischemic stroke via COX-2 with the Keap1/Nrf2 and MAPK pathways. Eur. J. Pharmacol. 1001, 177773 (2025).