An oxylipin
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(±)9,10-DiHODE

Item No. 35856

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9R,10R-dihydroxy-12Z,15Z-octadecadienoic acid
CAS Number
1400693-71-1
Synonyms
  • (±)9,10-dihydroxy-12(Z),15(Z)-ODE
  • (±)9,10-dihydroxy-cis-12,15-Octadecadienoic Acid
  • (±)9,10-Dihydroxyoctadecadienoic Acid
  • FA 18:2;O2
Molecular Formula
C18H32O4
Formula Weight
312.4
Purity
≥95%
Formulation (Request formulation change)
A 100 µg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
Chloroform: Sparingly soluble: 1-10 mg/mlDichloromethane: Sparingly soluble: 1-10 mg/mlEthanol: 10 mg/ml
SMILES
CC/C=C\C/C=C\C[C@@H](O)[C@H](O)CCCCCCCC(O)=O
InChi Code
InChI=1S/C18H32O4/c1-2-3-4-5-7-10-13-16(19)17(20)14-11-8-6-9-12-15-18(21)22/h3-4,7,10,16-17,19-20H,2,5-6,8-9,11-15H2,1H3,(H,21,22)/b4-3-,10-7-/t16-,17-/m1/s1
InChi Key
QRHSEDZBZMZPOA-VLHUJMHNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    25 µg

    $61

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    50 µg

    $109

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    100 µg

    $206

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    500 µg

    $847

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    Product Description

    (±)9,10-DiHODE is an α-linolenic acid-derived oxylipin.1,2 It is formed from α-linolenic acid (Item Nos. 90210 | 21910) by cytochrome P450s (CYPs). Corpora luteal levels of 9,10-DiHODE are increased in pregnant cattle and low plasma levels of 9,10-DiHODE are associated with preterm labor before 34 weeks of gestation.3,2 Serum levels of 9,10-DiHODE are decreased in patients with hyperlipidemia.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Schuchardt, J.P., Schmidt, S., Kressel, G., et al. Comparison of free serum oxylipin concentrations in hyper- vs. normolipidemic men. Prostaglandins Leukot. Essent. Fatty Acids 89(1), 19-29 (2013).

    2. Svenvik, M., Raffetseder, J., Brudin, L., et al. Plasma oxylipin levels associated with preterm birth in preterm labor. Prostaglandins Leukot. Essent. Fatty Acids 166, 102251 (2021).

    3. Owen, M.P.T., Northrop, E.J., Rich, J.J.J., et al. Oxylipin concentrations in bovine corpora lutea during maternal recognition of pregnancy. Theriogenology 142, 384-389 (2020).