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8(R)-hydroxy-9(S)-Hexahydrocannabinol

Item No. 36251

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 8β-hydroxy-9β-Hexahydrocannabinol
  • 8β-hydroxy-9(S)-Hexahydrocannabinol
  • 8β-hydroxy-9β-HHC
  • 8β-hydroxy-9(S)-HHC
  • 8R-hydroxy-9(S)-HHC
Technical Information
Formal Name
[6aR-(6aα,8α,9α,10aβ)]-6a,7,8,9,10,10a-hexahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1,8-diol
CAS Number
36403-92-6
Molecular Formula
C21H32O3
Formula Weight
332.5
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
Acetone: 10 mg/mlMethanol: Soluble
λmax
210, 284 nm
SMILES
CC1(C)[C@@]2([H])[C@](C[C@H](C)[C@H](O)C2)([H])C3=C(C=C(CCCCC)C=C3O)O1
InChi Code
InChI=1S/C21H32O3/c1-5-6-7-8-14-10-18(23)20-15-9-13(2)17(22)12-16(15)21(3,4)24-19(20)11-14/h10-11,13,15-17,22-23H,5-9,12H2,1-4H3/t13-,15+,16+,17+/m0/s1
InChi Key
CIVSDEYXXUHBPV-RKTXRCNFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    8(R)-hydroxy-9(S)-Hexahydrocannabinol (Item No. 36251) is an analytical reference standard that is structurally similar to known phytocannabinoids. 8(R)-hydroxy-9(S)-Hexahydrocannabinol is a metabolite of hexahydrocannabinol (HHC).1 It induces stupor, ataxia, hypolocomotion, ptosis, and a crouched posture in rhesus monkeys.2 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Harvey, D.J., and Brown, N.K. In vitro metabolism of the equatorial C11-methyl isomer of hexahydrocannabinol in several mammalian species. Drug Metab. Dispos. 19(3), 714-716 (1991).

    2. Edery, H., Grunfeld, Y., Ben-Zvi, Z., et al. Structural requirements for cannabinoid activity. Ann. N. Y. Acad. Sci. 191(1), 40-53 (1971).

    Product Citations

    Lindbom, K., Norman, C., Baginski, S., et al. Human metabolism of the semi-synthetic cannabinoids hexahydrocannabinol, hexahydrocannabiphorol and their acetates using hepatocytes and urine samples. Drug Test Anal. (2024).