An internal standard for the quantification of thymine
Related Products
Alternative(s)
41172Thymine-13C5,15N2
Unlabeled Version(s)
38749Thymine
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Thymine-d4

Item No. 36329

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-(methyl-d3)pyrimidine-2,4(1H,3H)-dione-6-d
CAS Number
156054-85-2
Molecular Formula
C5H2D4N2O2
Formula Weight
130.1
Purity
≥99% (deuterated forms d1-d4)
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: slightly soluDMSO: 3 mg/mlEthanol: insolPBS (pH 7.2): insol
λmax
264 nm
SMILES
O=C1C(C([2H])([2H])[2H])=C([2H])NC(N1)=O
InChi Code
InChI=1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)/i1D3,2D
InChi Key
RWQNBRDOKXIBIV-MZCSYVLQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    50 mg

    $94

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    100 mg

    $168

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    250 mg

    $279

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    Product Description

    Thymine-d4 is intended for use as an internal standard for the quantification of thymine by GC- or LC-MS. Thymine is a pyrimidine base.1 It forms complementary base pairs with the purine adenine (Item No. 18148) in DNA.1 Thymine is produced by the catabolism of thymidine (Item No. 20519) via thymidine phosphorylase.2 It is replaced with uracil (Item No. 26088) in RNA.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ghannam, J.Y., Wang, J., and Jan, A. Biochemistry, DNA Structure. 1-5 (2021).

    2. Brown, N.S., and Bicknell, R. Thymidine phosphorylase, 2-deoxy-D-ribose and angiogenesis. Biochem. J. 334(Pt 1), 1-8 (1998).

    3. Banoub, J.H., Newton, R.P., Esmans, E., et al. Recent developments in mass spectrometry for the characterization of nucleosides, nucleotides, oligonucleotides, and nucleic acids. Chem. Rev. 105(5), 1869-1915 (2005).