A pyrimidine nucleoside
Related Products
Enantiomer(s)
21453Telbivudine
Labeled Version(s)
36322Thymidine-d4
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Thymidine

Item No. 20519

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(8S,9R,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
CAS Number
50-89-5
Synonyms
  • 2’-deoxy Thymidine
  • 2’-deoxy-5-methyl-Uridine
  • dT
  • 5-Methyldeoxyuridine
  • NSC 21548
  • Thymine deoxyriboside
Molecular Formula
C10H14N2O5
Formula Weight
242.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 16 mg/mlDMSO: 10 mg/mlPBS (pH 7.2): 5 mg/ml
λmax
266 nm
SMILES
CC1=CN([C@@H]2O[C@H](CO)[C@@H](O)C2)C(NC1=O)=O
InChi Code
InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1
InChi Key
IQFYYKKMVGJFEH-XLPZGREQSA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 g

    $36

    Add

    5 g

    $70

    Add

    10 g

    $120

    Add

    25 g

    $209

    Add
    Product Description

    Thymidine is a pyrimidine nucleoside composed of a deoxyribose sugar and thymine base.1 It is phosphorylated by thymidine kinase 2 (TK2) in mitochondria to form deoxythymidine monophosphate (dTMP; Item No. 33549).2 Oral administration of thymidine in combination with deoxycytidine increases lifespan in a Tk2 H126N knock-in mouse model of TK2 deficiency.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Berg, J.M., Tymoczko, J.L., and Stryer, L. Biochemistry. (2002).

    2. Lopez-Gomez, C., Levy, R.J., Sanchez-Quintero, M.J., et al. Deoxycytidine and deoxythymidine treatment for thymidine kinase 2 deficiency. Ann. Neurol. 81(5), 641-652 (2017).