A metabolite of L-phenylalanine
Related Products
Parent Compound(s)
31498L-Phenylalanine
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2-Phenylacetamide

Item No. 36364

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
benzeneacetamide
CAS Number
103-81-1
Synonyms
  • NSC 1877
  • α-Toluamide
Molecular Formula
C8H9NO
Formula Weight
135.2
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 2 mg/mlDMSO: 2 mg/mlEthanol: 10 mg/ml
SMILES
O=C(CC1=CC=CC=C1)N
InChi Code
InChI=1S/C8H9NO/c9-8(10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,9,10)
InChi Key
LSBDFXRDZJMBSC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 g

    $32

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    50 g

    $118

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    100 g

    $217

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    250 g

    $502

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    Cayman Chemical
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    OBESITY RESEARCH SOLUTIONS
    Product Description

    2-Phenylacetamide is a metabolite of L-phenylalanine (Item No. 31498).1,2 It increases the proliferation of MCF-7 cells, an effect that can be blocked by the estrogen receptor (ER) antagonist ICI 182780 (fulvestrant; Item No. 10011269).3 It also increases the levels of luteinizing hormone and estrogen and the expression of estrogen receptor α (ERα) and ERβ in the uterus of immature female mice. Urinary levels of 2-phenylacetamide are increased in male obese patients compared with non-obese males.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yu, H.-T., Fu, X.-Y., Xu, B., et al. Untargeted metabolomics approach (UPLC-Q-TOF-MS) explores the biomarkers of serum and urine in overweight/obese young men. Asia Pac. J. Clin. Nutr. 27(5), 1067-1076 (2018).

    2. Guan, Y., Hu, W., Xu, Y., et al. Metabolomics and physiological analyses validates previous findings on the mechanism of response to wounding stress of different intensities in broccoli. Food Res. Int. 140, 110058 (2021).

    3. Zeng, M., Li, M., Li, M., et al. 2-Phenylacetamide isolated from the seeds of Lepidium apetalum and its estrogen-like effects in vitro and in vivo. Molecules 23(9), 2293 (2018).