A metabolite of trans-cinnamic acid
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Cinnamoylglycine

Item No. 36378

Technical Information
Formal Name
N-(1-oxo-3-phenyl-2-propen-1-yl)-glycine
CAS Number
16534-24-0
Molecular Formula
C11H11NO3
Formula Weight
Purity
≥98%
A solid
DMF: 15 mg/mlDMSO: 25 mg/mlEthanol: 1 mg/ml
λmax
205, 217, 223, 274 nm
SMILES
O=C(CNC(C=CC1=CC=CC=C1)=O)O
InChi Code
InChI=1S/C11H11NO3/c13-10(12-8-11(14)15)7-6-9-4-2-1-3-5-9/h1-7H,8H2,(H,12,13)(H,14,15)
InChi Key
YAADMLWHGMUGQL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Cinnamoylglycine is a metabolite of the unsaturated carboxylic acid trans-cinnamic acid.1 Urinary levels of cinnamoylglycine are decreased in a mouse model of gut microbiota colonization resistance induced by piperacillin (Item No. 20766) and tazobactam (Item Nos. 25679 | 17185).2 Serum levels of cinnamoylglycine are increased in patients with chronic kidney disease (CKD).3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nutley, B.P., Farmer, P., and Caldwell, J. Metabolism of trans-cinnamic acid in the rat and the mouse and its variation with dose. Food Chem. Toxicol. 32(10), 877-886 (1994).

    2. Obrenovich, M.E., Tima, M., Polinkovsky, A., et alTargeted metabolomics analysis identifies intestinal microbiota-derived urinary biomarkers of colonization resistance in antibiotic-treated mice. Antimicrob. Agents Chemother. 61(8), e00477-e00417 (2017).

    3. Boelaert, J., t'Kindt, R., Schepers, E., et alState-of-the-art non-targeted metabolomics in the study of chronic kidney disease. Metabolomics 10(3), 425-442 (2014).