An ω-alkynylated form of palmitoyl-CoA
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Palmitoyl Alkyne-Coenzyme A

Item No. 36470

Technical Information
Formal Name
coenzyme A, S-15-hexadecanoate
CAS Number
1941173-52-9
Synonyms
  • Click Tag™ Palmitoyl Alkyne-Coenzyme A
  • Palmitoyl Alkyne-CoA
Molecular Formula
C37H62N7O17P3S
Formula Weight
Purity
≥95%
A solid
Methanol: SolubleWater: Soluble
SMILES
O=C(CCNC([C@@](O)([H])C(C)(C)COP(OP(O)(OC[C@@H]1[C@@H](OP(O)(O)=O)[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O1)=O)(O)=O)=O)NCCSC(CCCCCCCCCCCCCC#C)=O
InChi Code
InChI=1S/C37H62N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-28(46)65-21-20-39-27(45)18-19-40-35(49)32(48)37(2,3)23-58-64(55,56)61-63(53,54)57-22-26-31(60-62(50,51)52)30(47)36(59-26)44-25-43-29-33(38)41-24-42-34(29)44/h1,24-26,30-32,36,47-48H,5-23H2,2-3H3,(H,39,45)(H,40,49)(H,53,54)(H,55,56)(H2,38,41,42)(H2,50,51,52)/t26-,30-,31-,32+,36-/m1/s1
InChi Key
GZHUDOCZNCSRDF-BBECNAHFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Palmitoyl alkyne-coenzyme A (palmitoyl alkyne-CoA) is a thioester of ω-alkynylated palmitic acid (Item No. 13266) and CoA (Item Nos. 16147 | 21499 | 21722). It has been used as a chemical reporter to label palmitoylated proteins via click chemistry using various probes, including biotin-azide (Item No. 13040) or 3-azido-7-hydroxycoumarin, in vitro and in vivo.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yap, M.C., Kostiuk, M.A., Martin, D.D.O., et alRapid and selective detection of fatty acylated proteins using ω-alkynyl-fatty acids and click chemistry. J. Lipid Res. 51(6), 1566-1580 (2010).