An endocrine disruptor and environmental contaminant
Related Products
Metabolite(s)
35857Bisphenol A-β-D-Glucuronide
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Bisphenol A

Item No. 36594

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4,4′-(1-methylethylidene)bis-phenol
CAS Number
80-05-7
Synonyms
  • BPA
  • NSC 1767
  • NSC 17959
Molecular Formula
C15H16O2
Formula Weight
228.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Sparingly soluble: 1-10 mg/ml
SMILES
OC1=CC=C(C(C)(C)C2=CC=C(C=C2)O)C=C1
InChi Code
InChI=1S/C15H16O2/c1-15(2,11-3-7-13(16)8-4-11)12-5-9-14(17)10-6-12/h3-10,16-17H,1-2H3
InChi Key
IISBACLAFKSPIT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 mg

    $48

    Add

    1 g

    $91

    Add

    5 g

    $156

    Add

    10 g

    $192

    Add
    Cayman Chemical
    Visit Our Environmental Toxicology Resource Center

    Explore additional resources to study natural toxins, pollutants including PFAS and 6-PPD-Q, and their biological effects.

    ENVIRONMENTAL TOXICOLOGY TOOLS & SERVICES
    Product Description

    Bisphenol A (BPA) is an endocrine disruptor and environmental contaminant.1,2 It has estrogenic activity in vitro, stimulates uterine, vaginal, and mammary growth and differentiation in rats, and reduces reproduction in zebrafish.1,3,4,5 Prenatal exposure to BPA disrupts metabolic regulation, leading to increased food intake, body and liver weight, and serum insulin levels in adult mice.6 BPA has been found in surface water, soil, and air samples, wildlife tissue samples, and human urine.2 Formulations containing BPA have been used in the production of plastics, fire retardants, and coatings.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Matthews, J.B., Twomey, K., and Zacharewski, T.R. In vitro and in vivo interactions of bisphenol A and its metabolite, bisphenol A glucuronide, with estrogen receptors α and β. Chem. Res. Toxicol. 14(2), 149-157 (2001).

    2. Corrales, J., Kristofco, L.A., Steele, W.B., et al. Global assessment of bisphenol A in the environment: Review and analysis of its occurrence and bioaccumulation. Dose Response 13(3), 1559325815598308 (2015).

    3. Krishnan, A.V., Stathis, P., Permuth, S.F., et al. Bisphenol-A: An estrogenic substance is released from polycarbonate flasks during autoclaving. Endocrinology 132(6), 2279-2286 (1993).

    4. Ben-Jonathan, N., and Steinmetz, R. Xenoestrogens: The emerging story of bisphenol A. Trends Endocrinol. Metab. 9(3), 124-128 (1998).

    5. Huang, Q., Liu, Y., Chen, Y., et al. New insights into the metabolism and toxicity of bisphenol A on marine fish under long-term exposure. Environ. Pollut. 242(Pt A), 914-921 (2018).

    6. Angle, B.M., Do, R.P., Ponzi, D., et al. Metabolic disruption in male mice due to fetal exposure to low but not high doses of bisphenol A (BPA): Evidence for effects on body weight, food intake, adipocytes, leptin, adiponectin, insulin and glucose regulation. Reprod. Toxicol. 42, 256-268 (2013).