An internal standard for the quantification of cystathionine
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Cystathionine-d4

Item No. 36610

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
S-(2-amino-2-carboxyethyl)-L-homocysteine-3,3,4,4-d4
Synonyms
  • Allocystathionine-d4
Molecular Formula
C7H10D4N2O4S
Formula Weight
226.3
Purity
≥99% deuterated forms (d1-d4)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: slightly
SMILES
OC(C(N)CSC([2H])([2H])C([2H])([2H])[C@H](N)C(O)=O)=O
InChi Code
InChI=1S/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5?/m0/s1/i1D2,2D2
InChi Key
ILRYLPWNYFXEMH-AMUFYZDFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $124

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    1 mg

    $234

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    Product Description

    Cystathionine-d4 is intended for use as an internal standard for the quantification of cystathionine (Item Nos. 17819 | 16061) by GC- or LC-MS. Cystathionine is an intermediate in the biosynthesis of cysteine that is composed of homocysteine and serine.1,2 It has four potential isomers, L-cystathionine, D-cystathionine, L-allocystathionine, and D-allocystathionine.3 Dietary administration of L-allocystathionine (0.74%) or the naturally occurring L-cystathionine (0.74%) substitute for cystine and increase the body weight of growing rats.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Steegborn, C., Clausen, T., Sondermann, P., et al. Kinetics and inhibition of recombinant human cystathionine γ-lyase. Toward the rational control of transsulfuration. The Journal of Biological Chemisty 274(18), 12675-12684 (1999).

    2. Finkelstein, J.D. The metabolism of homocysteine: Pathways and regulation. Eur. J. Pediatr. 157(Suppl 2), S40-S44 (1998).

    3. Anslow, W.P., Jr., Simmonds, S., and Du Vigneaud, V. The synthesis of the isomers of cystathionine and a study of their availability in sulfur metabolism. The Journal of Biological Chemisty 166(1), 35-45 (1946).