A perfluoroalkyl substance
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Perfluorodecanoic Acid

Item No. 37244

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-nonadecafluoro-decanoic acid
CAS Number
335-76-2
Synonyms
  • Nonadecafluorodecanoic Acid
  • PFDA
Molecular Formula
C10HF19O2
Formula Weight
514.1
Purity
≥80%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlEthanol: 2 mg/ml
SMILES
O=C(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(F)F)F)F)F)F)F)F)F)F)O
InChi Code
InChI=1S/C10HF19O2/c11-2(12,1(30)31)3(13,14)4(15,16)5(17,18)6(19,20)7(21,22)8(23,24)9(25,26)10(27,28)29/h(H,30,31)
InChi Key
PCIUEQPBYFRTEM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Cayman Chemical
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    Product Description

    Perfluorodecanoic acid is a perfluoroalkyl substance (PFAS).1 Chronic administration of perfluorodecanoic acid (25 mg/kg per day) induces weight loss and increases liver weight and lipid content in mice.2 Perfluorodecanoic acid (25 mg/kg per day) reduces mRNA expression of the genes encoding IL-1β, IL-18, and cellular inhibitor of apoptosis 2 (cIAP2), as well as caspase-1, -3, and -7 in mouse liver. It has been found in marine life and as a contaminant in surface water.1,3 Formulations containing perfluorodecanoic acid have been used commercially as wetting agents and flame retardants.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Li, Q., Wang, P., Wang, C., et al. A novel procedure for predicting chronic toxicities and ecological risks of perfluorinated compounds in aquatic environment. Environ. Res. 215(Pt 1), 114132 (2022).

    2. Li, K., Zhao, Q., Fan, Z., et al. The toxicity of perfuorodecanoic acid is mainly manifested as a defected immune function. Mol. Biol. Rep. 49, 4365–4376 (2022).

    3. Vi, P.T., Ngoc, N.T., Quang, P.D., et al. Perfluoroalkyl substances in freshwater and marine fish from northern Vietnam: Accumulation levels, profiles, and implications for human consumption. Mar. Pollut. Bull. 182, 113995 (2022).