A perfluoroalkyl substance and an insecticide
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N-ethyl Perfluorooctanesulfonamide

Item No. 37263

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-ethyl-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-1-octanesulfonamide
CAS Number
4151-50-2
Synonyms
  • N-ethyl FOSA
  • N-ethyl PFOSA
Molecular Formula
C10H6F17NO2S
Formula Weight
527.2
Purity
≥85%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlEthanol: 10 mg/ml
SMILES
O=S(NCC)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(F)F)F)F)F)F)F)F)F)=O
InChi Code
InChI=1S/C10H6F17NO2S/c1-2-28-31(29,30)10(26,27)8(21,22)6(17,18)4(13,14)3(11,12)5(15,16)7(19,20)9(23,24)25/h28H,2H2,1H3
InChi Key
CCEKAJIANROZEO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    N-ethyl Perfluorooctanesulfonamide (N-ethyl FOSA) is a perfluoroalkyl substance (PFAS) and an insecticide.1,2 It decreases the coupling efficiency, increases the rate of state four respiration, and uncouples mitochondrial oxidative phosphorylation in rat liver mitochondria when used at a concentration of 6.25 µM.3 N-ethyl FOSA reduces foraging activity of leaf-cutting ants (A. lundi) and reduces colony survival when applied in colonies as a 0.3% bait.2 It has been found in human blood and Arctic air samples.1,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Liu, D., Tang, B., Nie, S., et al. Distribution of per- and poly-fluoroalkyl substances and their precursors in human blood. J. Hazard. Mater. 441, 129908 (2023).

    2. Sabattini, J.A., Zanuncio, J.C., and Lemes, P.G. Chemical control of Acromyrmex lundi (Hymenoptera: Formicidae) in anthropic ecosystems. Pest. Manag. Sci. 78(7), 3155-3163 (2022).

    3. Starkov, A.A., and Wallace, K.B. Structural determinants of fluorochemical-induced mitochondrial dysfunction. Toxicol. Sci. 66(2), 244-252 (2002).

    4. Stock, N.L., Furdui, V.I., Muir, D.C.G., et al. Perfluoroalkyl contaminants in the Canadian Arctic: Evidence of atmospheric transport and local contamination. Environ. Sci. Technol. 41(10), 3529-3536 (2007).