An inactive analog of TH257
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TH263

Item No. 37295

Technical Information
Formal Name
N-(phenylmethyl)-4-[[(phenylmethyl)amino]sulfonyl]-benzamide
CAS Number
313520-94-4
Molecular Formula
C21H20N2O3S
Formula Weight
Purity
≥98%
A solid
DMF: 10 mg/mlDMSO: 10 mg/ml
λmax
242 nm
SMILES
O=C(C1=CC=C(S(=O)(NCC2=CC=CC=C2)=O)C=C1)NCC3=CC=CC=C3
InChi Code
InChI=1S/C21H20N2O3S/c24-21(22-15-17-7-3-1-4-8-17)19-11-13-20(14-12-19)27(25,26)23-16-18-9-5-2-6-10-18/h1-14,23H,15-16H2,(H,22,24)
InChi Key
QDGVJMITKNOVTP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    TH263 is an inactive analog of the inhibitor of LIM kinase 1 (LIMK1) and LIMK2 TH257 (Item No. 34236) that has been used as a negative control for the kinase activity of LIMK1 and LIMK2.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hanke, T., Mathea, S., Woortman, J., et alDevelopment and characterization of type I, type II, and type III LIM-kinase chemical probes. J. Med. Chem. 65(19), 13264-13287 (2022).