A paraben with diverse biological activities
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Isomer(s)
36314U-0521
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Propylparaben

Item No. 37417

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-hydroxy-benzoic acid, propyl ester
CAS Number
94-13-3
Synonyms
  • NSC 8511
  • NSC 23515
  • Propyl 4-hydoxybenzoate
  • Propyl p-hydoxybenzoate
  • Propyl para-hydoxybenzoate
Molecular Formula
C10H12O3
Formula Weight
180.2
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/ml
λmax
258 nm
SMILES
O=C(C1=CC=C(C=C1)O)OCCC
InChi Code
InChI=1S/C10H12O3/c1-2-7-13-10(12)8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3
InChi Key
QELSKZZBTMNZEB-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

    $29

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    5 g

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    10 g

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    25 g

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    Product Description

    Propylparaben is a paraben that has been found in R. chamaemorus and has diverse biological activities.1,2,3,4 It is active against several strains of P. stutzeri (MICs = 250-300 µg/ml).2 Propylparaben binds to estrogen receptors in a concentration-dependent manner, and administration of propylparaben (1% in the diet) decreases sperm counts and serum testosterone levels in rats.3,4 Propylparaben has been found in influent and effluent wastewater.5 Formulations containing propylparaben have been used as preservatives in cosmetics, food, and pharmaceuticals.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Baardseth, P., and Russwurm, H., Jr. Content of some organic acids in cloudberry (Rubus chamaemorus L.). Food Chem. 3(1), 43-46 (1978).

    2. Tattawasart, U., Maillard, J.-Y., Furr, J.R., et al. Comparative responses of Pseudomonas stutzeri and Pseudomonas aeruginosa to antibacterial agents. J. Appl. Microbiol. 87(3), 323-331 (1999).

    3. Routledge, E.J., Parker, J., Odum, J., et al. Some alkyl hydroxy benzoate preservatives (parabens) are estrogenic. Toxicol. Appl. Pharmacol. 153(1), 12-19 (1998).

    4. Oishi, S. Effects of propyl paraben on the male reproductive system. Food Chem. Toxicol. 40(12), 1807-1813 (2002).

    5. Wang, W., and Kannan, K. Fate of parabens and their metabolites in two wastewater treatment plants in New York state, United States. Environ. Sci. Technol. 50(3), 1174-1181 (2016).