A racemic mixture of eicosadienoic acid metabolites
Related Products
Isomer(s)
3750511(R)-HEDE 3751011(S)-HEDE
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(±)11-HEDE

Item No. 37500

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
11-hydroxy-12E,14Z-eicosadienoic acid
CAS Number
5598-37-8
Synonyms
  • 11-hydroxy-12,14-Eicosadienoic Acid
Molecular Formula
C20H36O3
Formula Weight
324.5
Purity
≥98%
Formulation (Request formulation change)
A 250 µg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 50 mg/mlDMSO: 50 mg/mlEthanol: 50 mg/mlPBS pH 7.2: 1 mg/ml
λmax
236 nm
SMILES
CCCCC/C=C\C=C/C(O)CCCCCCCCCC(=O)O
InChi Code
InChI=1S/C20H36O3/c1-2-3-4-5-7-10-13-16-19(21)17-14-11-8-6-9-12-15-18-20(22)23/h7,10,13,16,19,21H,2-6,8-9,11-12,14-15,17-18H2,1H3,(H,22,23)/b10-7-,16-13+
InChi Key
HDMIRVFIVOGVIC-YTLDOUCOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    25 µg

    $49

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    50 µg

    $93

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    100 µg

    $171

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    250 µg

    $400

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    Product Description

    (±)11-HEDE is a racemic mixture of the monohydroxy fatty acids 11(S)-HEDE (Item No. 37510) and 11(R)-HEDE (Item No. 37505). 11-HEDE is formed from eicosadienoic acid by cyclooxygenase (COX) and in macrophages.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hemler, M.E., Crawford, C.G., and Lands, W.E.M. Lipoxygenation activity of purified prostaglandin-forming cyclooxygenase. Biochemistry 17(9), 1772-1779 (1978).

    2. Rabinovitch, H., Durand, J., Gualde, N., et al. Metabolism of polyunsaturated fatty acids by mouse peritoneal macrophages: The lipoxygenase metabolic pathway. Agents Actions 11(6-7), 580-583 (1981).