An internal standard for the quantification of methyl parathion
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Unlabeled Version(s)
25786Methyl Parathion
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Methyl Parathion-d6

Item No. 37894

Technical Information
Formal Name
phosphorothioic acid, O,O-di(methyl-d3) O-(4-nitrophenyl) ester
CAS Number
96740-32-8
Molecular Formula
C8H4D6NO5PS
Formula Weight
Purity
≥99% deuterated forms (d1-d6)
Formulation
A 10 mg/ml solution in chloroform
Chloroform: Slightly solubleMethanol: Slightly soluble
SMILES
S=P(OC([2H])([2H])[2H])(OC([2H])([2H])[2H])OC1=CC=C([N+]([O-])=O)C=C1
InChi Code
InChI=1S/C8H10NO5PS/c1-12-15(16,13-2)14-8-5-3-7(4-6-8)9(10)11/h3-6H,1-2H3/i1D3,2D3
InChi Key
RLBIQVVOMOPOHC-WFGJKAKNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Methyl parathion-d6 is an internal standard for the quantification of methyl parathion (Item No. 25786) by GC- or LC-MS. Methyl parathion is an organophosphate insecticide.1 Methyl parathion is lethal to lab strains and field isolates of tobacco budworm larvae (LD50s = 7 and 81.8-128.3 μg/g, respectively).2 It reduces the number of stink bugs (C. sayi) caught per 100 net sweeps when applied to alfalfa fields at a concentration of 0.4 pounds per acre.3 Methyl parathion increases sister chromatid exchange (SCE) in a concentration-dependent manner and induces cell cycle arrest at the M1 phase in V79 cells at a concentration of 40 μg/ml.4 It is toxic to rats (LD50 = 14 mg/kg).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Guo, J.-X., Wu, J.J.-Q., Wight, J.B., et alMechanistic insight into acetylcholinesterase inhibition and acute toxicity of organophosphorus compounds: A molecular modeling study. Chem. Res. Toxicol. 19(2), 209-216 (2006).

    2. Martinez-Carrillo, J.L., and Reynolds, H.T. Dosage-mortality studies with pyrethroids and other insecticides on the tobacco budworm (Lepidoptera: Noctuidae) from the Imperial Valley, California. J. Econ. Entomol. 76(5), 983-986 (1983).

    3. Reynolds, H.T., Stern, V.M., Fukoto, T.R., et alPotential use of Dylox and other insecticides in a control program for field crop pests in California. J. Econ. Entomol. 53(1), 72-78 (1960).

    4. Chen, H.H., Hsueh, J.L., Sirianni, S.R., et alInduction of sister-chromatid exchanges and cell cycle delay in cultured mammalian cells treated with eight organophosphorus pesticides. Mutat. Res. 88(3), 307-316 (1981).