An essential amino acid
Related Products
Isomer(s)
34029L-Norvaline
Labeled Version(s)
34830L-Valine-d8
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L-Valine

Item No. 38709

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
72-18-4
Synonyms
  • (+)-Valine
  • (S)-Valine
  • NSC 76038
Molecular Formula
C5H11NO2
Formula Weight
117.1
Purity
≥90%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: Soluble
SMILES
O=C([C@H](C(C)C)N)O
InChi Code
InChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1
InChi Key
KZSNJWFQEVHDMF-BYPYZUCNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    100 g

    $28

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    250 g

    $65

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    500 g

    $125

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    Product Description

    L-Valine is a branched-chain essential amino acid that is obtained via the diet.1 It is considered glucogenic due to its catabolism that ultimately forms succinyl-CoA, which enters the citric acid cycle.2 A deficiency in branched-chain dehydrogenase, the enzyme that catabolizes valine, isoleucine, and leucine, leads to maple syrup urine disease, a disorder characterized by progressive ketoacidosis, failure to thrive, neurological dysfunction, and, potentially, death.1,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Berg, J.M., Tymoczko, J.L., and Stryer, L. Biochemistry. (2002).

    2. Massey, K.A., Blakeslee, C.H., and Pitkow, H.S. A review of physiological and metabolic effects of essential amino acids. Amino Acids 14(4), 271-300 (1998).

    3. Farias, H.R., Gabriel, J.R., Cecconi, M.L., et al. The metabolic effect of α-ketoisocaproic acid: In vivo and in vitro studies. Metab. Brain Dis. 36(1), 185-192 (2021).