An ITP derivative
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Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

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8-bromo TNP-ITP (sodium salt)

Item No. 38818

Technical Information
Formal Name
((3a'R,4'R,6'R,6a'R)-4'-(8-bromo-6-oxo-3,6-dihydro-9H-purin-9-yl)-2,4,6-trinitro-3a',4',6',6a'-tetrahydrospiro[cyclohexane-1,2'-furo[3,4-d][1,3]dioxole]-2,5-dien-6'-yl)methyl triphosphate, tetrasodium salt
Synonyms
  • 8-bromo TNP-Inosine 5’-triphosphate
Molecular Formula
C16H11BrN7O20P3 • 4Na
Formula Weight
Purity
≥95%
A solution in water
Water: Soluble
SMILES
O=P(OP([O-])([O-])=O)([O-])OP(OC[C@H]1O[C@@H](N2C(Br)=NC3=C2NC=NC3=O)[C@@]4([H])[C@]1([H])OC5(C([N+]([O-])=O)=CC([N+]([O-])=O)C=C5[N+]([O-])=O)O4)([O-])=O.[Na+].[Na+].[Na+].[Na+]
InChi Code
InChI=1S/C16H15BrN7O20P3.4Na/c17-15-20-9-12(18-4-19-13(9)25)21(15)14-11-10(6(40-14)3-39-46(35,36)44-47(37,38)43-45(32,33)34)41-16(42-11)7(23(28)29)1-5(22(26)27)2-8(16)24(30)31;;;;/h1-2,4-6,10-11,14H,3H2,(H,35,36)(H,37,38)(H,18,19,25)(H2,32,33,34);;;;/q;4*+1/p-4/t5?,6-,10-,11-,14-,16?;;;;/m1..../s1
InChi Key
IFAVCEBVTCHIPL-XIQHJPNBSA-J
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    Product Description

    8-bromo TNP-ITP is a derivative of the nucleoside triphosphate ITP (Item No. 23063). A related derivative, TNP-GTP (Item No. 38570), displays an emission maximum of 552 nm upon excitation at 410 nm.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hiratsuka, T. A chromophoric and fluorescent analog of GTP, 2',3'-O-(2,4,6-trinitrocyclohexadienylidene)-GTP, as a spectroscopic probe for the GTP inhibitory site of liver glutamate dehydrogenase. The Journal of Biological Chemisty 260(8), 4784-4790 (1985).