A derivative of TNP-ATP
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Product Type

Biochemicals
Nucleotides/Nucleosides

2-methylthio TNP-ITP (sodium salt)

Item No. 38831

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(4'-(2-(methylthio)-6-oxo-3,6-dihydro-9H-purin-9-yl)-2,4,6-trinitro-3a'R,4'R,6'R,6a'R-tetrahydrospiro[cyclohexane-1,2'-furo[3,4-d][1,3]dioxole]-2,5-dien-6'-yl)methyl triphosphate, tetrasodium salt
Synonyms
  • 2-methylthio TNP-Inosine 5'-triphosphate
Molecular Formula
C17H14N7O20P3S • 4Na
Formula Weight
853.3
Purity
≥95%
Formulation (Request formulation change)
A solution in water
Solubility(Learn about Variance in Solubility)
Water: Soluble
SMILES
O=P(OP([O-])([O-])=O)([O-])OP(OC[C@H]1O[C@@H](N2C=NC3=C2NC(SC)=NC3=O)[C@@]4([H])[C@]1([H])OC5(C([N+]([O-])=O)=CC([N+]([O-])=O)C=C5[N+]([O-])=O)O4)([O-])=O.[Na+].[Na+].[Na+].[Na+]
InChi Code
InChI=1S/C17H18N7O20P3S.4Na/c1-48-16-19-13-10(14(25)20-16)18-5-21(13)15-12-11(7(40-15)4-39-46(35,36)44-47(37,38)43-45(32,33)34)41-17(42-12)8(23(28)29)2-6(22(26)27)3-9(17)24(30)31;;;;/h2-3,5-7,11-12,15H,4H2,1H3,(H,35,36)(H,37,38)(H,19,20,25)(H2,32,33,34);;;;/q;4*+1/p-4/t6?,7-,11-,12-,15-,17?;;;;/m1..../s1
InChi Key
JIQZTRNBVRXMFB-OOWSHYBDSA-J
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    800 µg

    $191

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    Product Description

    2-methylthio TNP-ITP (2-methylthio TNP-Inosine 5'-triphosphate) is a derivative of the fluorescent probe and purinergic P2X1, P2X3, and P2X2/3 receptor antagonist TNP-ATP (Item No. 20902). A related derivative, TNP-GTP (Item No. 38570), displays an emission maximum of 552 nm upon excitation at 410 nm.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hiratsuka, T. A chromophoric and fluorescent analog of GTP, 2',3'-O-(2,4,6-trinitrocyclohexadienylidene)-GTP, as a spectroscopic probe for the GTP inhibitory site of liver glutamate dehydrogenase. The Journal of Biological Chemisty 260(8), 4784-4790 (1985).