A quinazoline acaracide
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Fenazaquin

Item No. 38881

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[2-[4-(1,1-dimethylethyl)phenyl]ethoxy]-quinazoline
CAS Number
120928-09-8
Synonyms
  • GWN 1708
Molecular Formula
C20H22N2O
Formula Weight
306.4
Purity
≥95%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly soluble: 0.1 mg/mlEthanol: Slightly soluble: 0.1 mg/ml
SMILES
CC(C)(C)C(C=C1)=CC=C1CCOC2=NC=NC3=C2C=CC=C3
InChi Code
InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3
InChi Key
DMYHGDXADUDKCQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $47

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    50 mg

    $88

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    100 mg

    $158

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    Cayman Chemical
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    Product Description

    Fenazaquin is a quinazoline acaracide.1,2 It is an inhibitor of mitochondrial complex I, also known as NADH dehydrogenase (IC50 = 4 nM for the bovine enzyme).1 When applied near apiary food, fenazaquin (0.5 or 5 mg/strip) induces mite mortality without inducing honeybee death in mite-infested beehives.2 It reduces the number of immature and adult female mites on apple leaves in field studies when applied at a concentration of 100 or 200 ppm.3 Formulations containing fenazaquin have been used in the control of acaricides in agriculture.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wood, E., Latli, B., and Casida, J.E. Fenazaquin acaricide specific binding sites in NADH: Ubiquinone oxidoreductase and apparently the ATP synthase stalk. Pest. Biochem. Phys. 54(2), 135-145 (1996).

    2. Bahreini, R., Nasr, M., Docherty, C., et al. Miticidal activity of fenazaquin and fenpyroximate against Varroa destructor, an ectoparasite of Apis mellifera. Pest Manag. Sci. 78(4), 1686-1697 (2022).

    3. Solomon, M.G., Fitzgerald, J.D., and Ridout, M.S. Fenazaquin, a selective acaricide for use in IPM in apple in the UK. Crop Prot. 12(4), 255-258 (1993).