An internal standard for the quantification of ω-3 arachidonic acid
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Unlabeled Version(s)
90011ω-3 Arachidonic Acid
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ω-3 Arachidonic Acid-d8

Item No. 390011

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
8Z,11Z,14Z,17Z-eicosatetraenoic-8,9,11,12,14,15,17,18-d8 acid
CAS Number
2692624-30-7
Synonyms
  • ω-3 AA-d8
  • FA 20:4-d8
Molecular Formula
C20H24D8O2
Formula Weight
312.5
Purity
≥99% deuterated forms (d1-d8)
Formulation
A 1 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
0.1 M Na2CO3: 1.7 mg/mlDMF: >100 mg/mlDMSO: >100 mg/mlEthanol: Miscible
SMILES
CC/C=C\C/C=C\C/C=C\C/C=C\CCCCCCC(=O)O
InChi Code
InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13H,2,5,8,11,14-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-/i3D,4D,6D,7D,9D,10D,12D,13D
InChi Key
HQPCSDADVLFHHO-LDWVABASSA-N
Side Chain Carbon Sum
20:4
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    100 µg

    $36

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    500 µg

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    1 mg

    $169

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    Product Description

    ω-3 Arachidonic acid-d8 contains eight deuterium atoms at the 8, 9, 11, 12, 14, 15, 17, and 18 positions. It is intended for use as an internal standard for the quantification of ω-3 arachidonic acid by GC- or LC-mass spectrometry. ω-3 Arachidonic acid is a rare polyunsaturated fatty acid found in trace amounts in dietary sources. ω-3 fatty acids are now known to be essential for infant growth and development and to protect against heart disease, thrombosis, hypertension, and inflammatory and autoimmune disorders.1 In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki value of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Neufeld, E.J., Sprecher, H., Evans, R.W., et al. Fatty acid structural requirements for activity of arachidonoyl-CoA synthetase. J. Lipid Res. 25(3), 288-293 (1984).

    2. Simopoulos, A.P. Omega-3 Fatty acids in health and disease and in growth and development. Am. J. Clin. Nutr. 54(3), 438-463 (1991).