A rare, natural 20:4 ω-3 polyunsaturated fatty acid
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Isomer(s)
15198Juniperonic Acid
Labeled Version(s)
390011ω-3 Arachidonic Acid-d8
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ω-3 Arachidonic Acid

Item No. 90011

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
8Z,11Z,14Z,17Z-eicosatetraenoic acid
CAS Number
24880-40-8
Synonyms
  • ω-3 AA
  • FA 20:4
Molecular Formula
C20H32O2
Formula Weight
304.5
Purity
≥98%
Formulation
A 5 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
0.1 M Na2CO3: 1.7 mg/mlDMF: >100 mg/mlDMSO: >100 mg/mlEthanol: Miscible
SMILES
CC/C=C\C/C=C\C/C=C\C/C=C\CCCCCCC(=O)O
InChi Code
InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13H,2,5,8,11,14-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-
InChi Key
HQPCSDADVLFHHO-LTKCOYKYSA-N
Side Chain Carbon Sum
20:4
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $74

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    1 mg

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    5 mg

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    10 mg

    $1,095

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    Product Description

    ω-3 Arachidonic acid is a rare PUFA found in trace amounts in dietary sources. ω-3 Fatty acids are now known to be essential for infant growth and development and protect against heart disease, thrombosis, hypertension, and inflammatory and autoimmune disorders.1 In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Simopoulos, A.P. Omega-3 Fatty acids in health and disease and in growth and development. Am. J. Clin. Nutr. 54(3), 438-463 (1991).

    2. Neufeld, E.J., Sprecher, H., Evans, R.W., et al. Fatty acid structural requirements for activity of arachidonoyl-CoA synthetase. J. Lipid Res. 25(3), 288-293 (1984).

    Product Citations

    Zhang, L.J., Salekeen, R., Soto-Palma, C., et al. Article polyunsaturated lipid senolytics exploit a ferroptotic vulnerability in senescent cells. Cell Press Blue 1(1), 100004 (2026).

    Caires, R., Sierra-Valdez, F.J., Millet, J.R.M., et al. Omega-3 fatty acids modulate TRPV4 function through plasma membrane remodeling. Cell Reports 21, 245-258 (2017).