An internal standard for the quantification of pyridaben
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Unlabeled Version(s)
25821Pyridaben
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Pyridaben-d13

Item No. 39259

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-chloro-2-(1,1-dimethylethyl)-5-[[[4-(1,1-dimethylethyl-d9)phenyl-2,3,5,6-d4]methyl]thio]-3(2H)-pyridazinone
CAS Number
2468638-05-1
Synonyms
  • Damanlin-d13
Molecular Formula
C19H12ClD13N2OS
Formula Weight
378.0
Purity
≥99% deuterated forms (d1-d13)
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly soluble
SMILES
ClC(C(N(C(C)(C)C)N=C1)=O)=C1SCC2=C([2H])C([2H])=C(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C([2H])=C2[2H]
InChi Code
InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3/i1D3,2D3,3D3,7D,8D,9D,10D
InChi Key
DWFZBUWUXWZWKD-HGCMJWCISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

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    Product Description

    Pyridaben-d13 is intended for use as an internal standard for the quantification of pyridaben (Item No. 25821) by GC- or LC-MS. Pyridaben is a METI acaricide that inhibits mitochondrial electron transport at complex I (METI; Ki = 0.36 nmol/mg protein in rat brain mitochondria).1 It is active against a variety of mites, inducing 100% mortality of C. malaccensis, D. farina, and T. putrescentia when administered via filter paper contact at doses of 25, 100, and 200 mg/m3, respectively.2 Pyridaben is toxic to rats when administered orally (LD50s = 570 and 1,100 for female and male rats, respectively) and via inhalation (LD50s = 0.62 and 0.66 mg/L for female and male rats, respectively).3 Formulations containing pyridaben have been used in the control of mites in agriculture.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Navarro, A., Bández, M.J., Gómez, C., et al. Effects of rotenone and pyridaben on complex I electron transfer and on mitochondrial nitric oxide synthase functional activity. J. Bioenerg. Biomembr. 42(5), 405-412 (2010).

    2. Takahashi, M., Shono, T., and Umehara, T. Efficacy of pyridaben against three kinds of mites, Cheyletus malaccensis, Dermatophagoides farinae and Tyrophagus putrescentiae. Jpn. J. Sanit. Zool. 41(3), 257-260 (1990).

    3. Igarashi, H., and Sakamoto, S. Summary of toxicity studies with pyridaben. J. Pest. Scien. 19(4), S243-S251 (1994).