A phospholipid
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Cardiolipin (16:1/16:1/16:1/16:1) (sodium salt)

Item No. 39281

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9-hexadecenoic acid, 1,1′,1′′,1′′′-[(2R,14R)-5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diophosphapentadecane-1,2,14,15-tetrayl] ester, disodium salt
CAS Number
2260669-34-7
Synonyms
  • 16:1 Cardiolipin
  • 64:4-CL
  • Diphosphatidylglycerol (16:1)
  • Tetrapalmitoleoyl Cardiolipin
Molecular Formula
C73H132O17P2 • 2Na
Formula Weight
1389.8
Purity
≥95%
Formulation (Request formulation change)
A 5 mg/ml solution in chloroform
Solubility(Learn about Variance in Solubility)
Chloroform: Soluble
SMILES
[O-]P(OCC(O)COP([O-])(OC[C@@H](COC(CCCCCCC/C=C\CCCCCC)=O)OC(CCCCCCC/C=C\CCCCCC)=O)=O)(OC[C@@H](COC(CCCCCCC/C=C\CCCCCC)=O)OC(CCCCCCC/C=C\CCCCCC)=O)=O.[Na+].[Na+]
InChi Code
InChI=1S/C73H134O17P2.2Na/c1-5-9-13-17-21-25-29-33-37-41-45-49-53-57-70(75)83-63-68(89-72(77)59-55-51-47-43-39-35-31-27-23-19-15-11-7-3)65-87-91(79,80)85-61-67(74)62-86-92(81,82)88-66-69(90-73(78)60-56-52-48-44-40-36-32-28-24-20-16-12-8-4)64-84-71(76)58-54-50-46-42-38-34-30-26-22-18-14-10-6-2;;/h25-32,67-69,74H,5-24,33-66H2,1-4H3,(H,79,80)(H,81,82);;/q;2*+1/p-2/b29-25-,30-26-,31-27-,32-28-;;/t68-,69-;;/m1../s1
InChi Key
YAYWCGRIYVZIGJ-RWGXQKRHSA-L
Side Chain Carbon Sum
64:4
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 mg

    $142

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    Product Description

    Cardiolipin (16:1/16:1/16:1/16:1) is an anionic phospholipid containing the long-chain monounsaturated fatty acid (MUFA) palmitoleic acid (Item Nos. 10009871 | 21911). It increases the activation of, and cytokine production by, DN32.D3 type 1 natural killer T (NKT) cells when incubated with L-M(TK-) mouse fibroblasts expressing the lipid antigen-presenting molecule CD1d (L-CD1d cells) prior to their co-culture with the DN32.D3 NKT cells.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lee, S., Sun, W., and Webb, T.J. Sphingosine kinase blockade leads to increased natural killer T cell responses to mantle cell lymphoma. Cells 9(4), 1030 (2020).