An ω-7 monounsaturated fatty acid
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Palmitoleic Acid (sodium salt)

Item No. 21911

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9Z-hexadecenoic acid, monosodium salt
CAS Number
6610-24-8
Synonyms
  • C16:1(9Z)
  • C16:1 n-7
  • FA 16:1
  • (9Z)-Hexadecenoic Acid
  • cis-Palmitoleic Acid
Molecular Formula
C16H29O2 • Na
Formula Weight
276.4
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Ethanol: 1.5 mg/mlEthanol:PBS (pH 7.2) (1:5): 0.5 mg/ml
SMILES
CCCCCC/C=C\CCCCCCCC([O-])=O.[Na+]
InChi Code
InChI=1S/C16H30O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18;/h7-8H,2-6,9-15H2,1H3,(H,17,18);/q;+1/p-1/b8-7-;
InChi Key
AQADNICIQOBXGR-CFYXSCKTSA-M
Side Chain Carbon Sum
16:1
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    100 mg

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    Product Description

    Palmitoleic acid is an ω-7 monounsaturated fatty acid that has been found in macadamia and sea buckthorn oils.1,2 It increases basal and insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) protein levels in 3T3-L1 adipocytes when used at a concentration of 200 µM.3 Ex vivo, palmitoleic acid (300 mg/kg per day) increases glucose uptake and aerobic and anaerobic glycolysis and reduces de novo fatty acid synthesis and activity of the lipogenic enzymes ATP citrate lyase (ACL) and glucose-6-phosphate dehydrogenase (G6PDH) in isolated murine adipocytes. Dietary administration of palmitoleic acid (300 mg/kg) reduces high-fat diet-induced insulin resistance and liver inflammation in mice.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yang, B., and Kallio, H.P. Fatty acid composition of lipids in sea buckthorn (Hippophaë rhamnoids L.) berries of different origins. J. Agric. Food Chem. 49(4), 1939-1947 (2001).

    2. Fard, A.M., Turner, A.G., and Willett, G.D. High-resolution electrospray-ionization fourier-transform ion cyclotron resonance and gas chromatography-mass spectrometry of macadamia nut oil. Aus. J. Chem. 56(5), 499-508 (2003).

    3. Bolsoni-Lopes, A., Festuccia, W.T., Chimin, P., et al. Palmitoleic acid (n-7) increases white adipocytes GLUT4 content and glucose uptake in association with AMPK activation. Lipids Health Dis. 13(199), 1-10 (2014).

    4. Souza, C.O., Teixeira, A.A.S., Lima, E.A., et al. Palmitoleic acid (N-7) attenuates the immunometabolic disturbances caused by a high-fat diet independently of PPARɑ. Mediators Inflamm. 582197 (2014).