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ENVIRONMENTAL TOXICOLOGY TOOLS & SERVICESThiacloprid-d4 is intended for use as an internal standard for the quantification of thiacloprid (Item No. 25824) by GC- or LC-MS. Thiacloprid is a neonicotinoid insecticide.1 It is an antagonist of nicotinic acetylcholine receptors (nAChRs; IC50 = 2.7 nM for the D. melanogaster enzyme). Thiacloprid is lethal to D. melanogaster (LD50 = 0.03 mg/kg). It is toxic to mice (LD50 = 28 mg/kg).1
WARNING This product is not for human or veterinary use.
1. Neonicotinoid insecticides: Molecular features conferring selectivity for insect versus mammalian nicotinic receptors. J. Agric. Food Chem. 48(12), 6016-6024 (2000).