An internal standard for the quantification of flonicamid
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Unlabeled Version(s)
25608Flonicamid
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Flonicamid-15N,18O

Item No. 39578

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(cyanomethyl)-4-(trifluoromethyl)-3-pyridinecarboxamide-15N-18O
CAS Number
2483830-60-8
Molecular Formula
C9H6F3N2[15N][18O]
Formula Weight
232.2
Purity
≥98%
Formulation
A solution in methanol
Solubility(Learn about Variance in Solubility)
Methanol: soluble
SMILES
FC(F)(C1=C(C([15NH]CC#N)=[18O])C=NC=C1)F
InChi Code
InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)/i15+1,16+2
InChi Key
RLQJEEJISHYWON-ZNQGSEOTSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1.2 ml

    $567

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    Product Description

    Flonicamid-15N,18O is intended for use as an internal standard for the quantification of flonicamid (Item No. 25608) by GC- or LC-MS. Flonicamid is a pyridinecarboxamide insecticide.1 It inhibits the brown planthopper (N. lugens) inward-rectifying potassium channel Kir1 (IC50 = 0.64 µM). Flonicamid (100 µg/ml) inhibits aphid (M. persicae) salivation and sap ingestion during feeding on Japanese radish leaves.2 It induces toxicity in the aphid species A. gossypii, R. padi, S. graminum, and L. erysimi (LC50s = 0.64, 0.74, 0.78, and 2.01 µg/ml, respectively) and rats (LD50 = ≥844 mg/kg).3,2 Formulations containing flonicamid have been used for the control of pest insects in agriculture.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ren, M., Niu, J., Hu, B., et al. Block of Kir channels by flonicamid disrupts salivary and renal excretion of insect pests. Insect Biochem. Mol. Biol. 99, 17-26 (2018).

    2. Morita, M., Ueda, T., Yoneda, T., et al. Flonicamid, a novel insecticide with a rapid inhibitory effect on aphid feeding. Pest. Manag. Sci. 63(10), 969-973 (2007).

    3. Morita, M., Yoneda, T., and Akiyoshi, N. Research and development of a novel insecticide, flonicamid. J. Pestic. Sci. 39(3), 179-180 (2014).