A β-adrenergic receptor agonist
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Deterenol (hydrochloride)

Item No. 39583

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-hydroxy-α-[[(1-methylethyl)amino]methyl]-benzenemethanol, monohydrochloride
CAS Number
23239-36-3
Synonyms
  • Isopropyloctopamine
  • Isopropylnorsynephrine
Molecular Formula
C11H17NO2 • HCl
Formula Weight
231.7
Purity
≥95%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly solubleDMSO: SolubleWater: Slightly soluble
SMILES
OC1=CC=C(C(CNC(C)C)O)C=C1.Cl
InChi Code
InChI=1S/C11H17NO2.ClH/c1-8(2)12-7-11(14)9-3-5-10(13)6-4-9;/h3-6,8,11-14H,7H2,1-2H3;1H
InChi Key
KTOGVIILDSYTNS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $50

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    5 mg

    $186

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    10 mg

    $248

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    25 mg

    $557

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    Cayman Chemical
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    OBESITY RESEARCH SOLUTIONS
    Product Description

    Deterenol is a non-selective β-adrenergic receptor (β-AR) agonist.1 It increases tension in isolated right and left guinea pig atria and trachea (IC50s = 0.411, 1.44, and 8.37 µM, respectively), which endogenously express β-ARs, but has no effect on isolated rabbit aortic strips, which express α-ARs. Deterenol induces lipolysis in human adipocytes.2 Formulations containing deterenol have previously been used as weight loss and sports supplements.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Anderson, W.G. The sympathomimetic activity of N-isopropyloctopamine in vitro. J. Pharmacol. Exp. Ther. 225(3), 553-558 (1983).

    2. Mercader, J., Wanecq, E., Chen, J., et al. Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium. J. Physiol. Biochem. 67(3), 443-452 (2011).