A dipeptide
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Glutaurine

Item No. 39586

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(2-sulfoethyl)-L-glutamine
CAS Number
56488-60-9
Synonyms
  • γ-Glutamyl Taurine
  • γ-L-Glutamyl Taurine
Molecular Formula
C7H14N2O6S
Formula Weight
254.3
Purity
≥90%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
SMILES
OC([C@@H](N)CCC(NCCS(=O)(O)=O)=O)=O
InChi Code
InChI=1S/C7H14N2O6S/c8-5(7(11)12)1-2-6(10)9-3-4-16(13,14)15/h5H,1-4,8H2,(H,9,10)(H,11,12)(H,13,14,15)/t5-/m0/s1
InChi Key
WGXUDTHMEITUBO-YFKPBYRVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $60

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    50 mg

    $112

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    100 mg

    $211

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    250 mg

    $468

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    Product Description

    Glutaurine is a dipeptide composed of L-glutamic acid (Item No. 30377) and taurine (Item No. 27031) that has been found in rat brain.1 It is formed from glutathione and taurine by γ-glutamyl transpeptidase. Glutaurine enhances potassium-induced release of L-glutamate and inhibits kainate-induced formation of cGMP in isolated mouse cerebral cortical slices when used at concentrations of 0.1 and 1 mM, respectively.2 It decreases plasma levels of triiodothyronine (T3) and increases plasma thyroid-stimulating hormone (TSH) levels in rats when administered at a dose of 600 µg/kg.3 Glutaurine (50 µg/animal, p.o.) prevents electroconvulsive shock-induced amnesia in rats.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Török, K., Varga, V., Somogyi, J., et al. Formation of γ-glutamyl-taurine in the rat brain. Neurosci. Lett. 27(2), 145-149 (1981).

    2. Varga, V., Janáky, R., Marnela, K.-M., et al. Interactions of γ-L-glutamyltaurine with excitatory aminoacidergic neurotransmission. Neurochem. Res. 19(3), 243-248 (1994).

    3. Baskin, S.I., Bartuska, D., Thampi, N., et al. The effect of glutaurine on thyroid hormones in the rat. Neuropeptides 9(1), 45-50 (1987).

    4. Balazs, M., and Telegdy, G. Effects of glutaurine treatment on electroshock-induced amnesia. Antiamnesic action of glutaurine. Neuropeptides 12(2), 55-58 (1988).