An active metabolite of cinobufagin
Related Products
Isomer(s)
20798Marinobufagenin
Parent Compound(s)
19844Cinobufagin
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Desacetylcinobufagin

Item No. 39822

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5β)-14,15β-epoxy-3β,16β-dihydroxy-bufa-20,22-dienolide
CAS Number
4026-95-3
Synonyms
  • Deacetylcinobufagin
  • NSC 234203
Molecular Formula
C24H32O5
Formula Weight
400.5
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly solubleDMSO: Slightly solubleMethanol: Slightly soluble
SMILES
C[C@]12[C@@]3([C@@]4([H])[C@]([C@@]5([C@](C[C@H](CC5)O)([H])CC4)C)([H])CC2)[C@]([C@@H]([C@@H]1C(C=C6)=COC6=O)O)([H])O3
InChi Code
InChI=1S/C24H32O5/c1-22-9-7-15(25)11-14(22)4-5-17-16(22)8-10-23(2)19(13-3-6-18(26)28-12-13)20(27)21-24(17,23)29-21/h3,6,12,14-17,19-21,25,27H,4-5,7-11H2,1-2H3/t14-,15+,16+,17-,19+,20-,21-,22+,23-,24-/m1/s1
InChi Key
IXZHDDUFQVXHIL-UOAIQHMYSA-N
Origin
Plant/Bufonis Venenum
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $39

    Add

    5 mg

    $183

    Add

    10 mg

    $347

    Add
    Cayman Chemical
    Visit Our Cancer Resource Center
    Find Tools & Resources to Study the Hallmarks of Cancer
    • Cancer cell signaling & regulation
    • Cancer metabolism
    • Tumor microenvironment
    EXPLORE NOW
    Product Description

    Desacetylcinobufagin is an active metabolite of the cardiotonic steroid cinobufagin (Item No. 19844).1 It is cytotoxic to HepG2, K562, and HL-60 cells (IC50s = 51.2, 50.1, and 7.5 µM, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. He, X., Hu, H., Wu, Y., et al. Urinary metabolites of cinobufagin in rats and their antiproliferative activities. Nat. Prod. Res. 26(6), 489-499 (2012).