A derivative of vitamin A
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Viaminate

Item No. 40118

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[4-(ethoxycarbonyl)phenyl]-retinamide
CAS Number
53839-71-7
Molecular Formula
C29H37NO3
Formula Weight
447.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly SolubleDMSO: SolubleMethanol: Slightly Soluble
SMILES
CC(/C=C/C1=C(C)CCCC1(C)C)=C\C=C\C(C)=C\C(NC2=CC=C(C(OCC)=O)C=C2)=O
InChi Code
InChI=1S/C29H37NO3/c1-7-33-28(32)24-14-16-25(17-15-24)30-27(31)20-22(3)11-8-10-21(2)13-18-26-23(4)12-9-19-29(26,5)6/h8,10-11,13-18,20H,7,9,12,19H2,1-6H3,(H,30,31)/b11-8+,18-13+,21-10+,22-20+
InChi Key
VRSMJNVXOITYPE-FSDIUQKZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 mg

    $109

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    1 g

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    5 g

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    Cayman Chemical
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    Product Description

    Viaminate is a derivative of the retinoid vitamin A (Item No. 20241).1,2 It reverses keratinization of vitamin A-deficient primary hamster tracheal epithelial cells when used at a concentration of 10 nM.1 Viaminate (1.7-15 mg/kg, p.o.) reduces epidermal keratinization, oil accumulation, ear thickness and edema, and ear skin levels of Il-6, Il-1β, and Tnf-α in a rat model of acne induced by P. acnes.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Jaegar, E.P., Jurs, P.C., and Stouch, T.R. Structure-activity relationship studies of retinoid cancer inhibition. Eur. J. Med. Chem. 28(4), 275-290 (1993).

    2. Cao, J., Xu, M., Zhu, L., et al. Viaminate ameliorates Propionibacterium acnes-induced acne via inhibition of the TLR2/NF-κB and MAPK pathways in rats. Naunyn Schmiedebergs Arch Pharmacol. 396(7), 1487-1500 (2023).