A nucleoside building block
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N4-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine-3′-cyanoethyl Phosphoramidite

Item No. 40293

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-cytidine
CAS Number
102212-98-6
Synonyms
  • DMT-dc(Bz) phosphoramidite​
Molecular Formula
C46H52N5O8P
Formula Weight
833.9
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlEthanol: Soluble: ≥10 mg/ml
SMILES
CC(C)N(C(C)C)P(OCCC#N)O[C@@H](C[C@H](N1C(N=C(C=C1)NC(C2=CC=CC=C2)=O)=O)O3)[C@H]3COC(C4=CC=C(C=C4)OC)(C5=CC=CC=C5)C6=CC=C(C=C6)OC
InChi Code
InChI=1S/C46H52N5O8P/c1-32(2)51(33(3)4)60(57-29-13-27-47)59-40-30-43(50-28-26-42(49-45(50)53)48-44(52)34-14-9-7-10-15-34)58-41(40)31-56-46(35-16-11-8-12-17-35,36-18-22-38(54-5)23-19-36)37-20-24-39(55-6)25-21-37/h7-12,14-26,28,32-33,40-41,43H,13,29-31H2,1-6H3,(H,48,49,52,53)/t40-,41+,43+,60?/m0/s1
InChi Key
PGTNFMKLGRFZDX-SALLYJDFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 g

    $28

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    5 g

    $97

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    Product Description

    N4-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine-3′-cyanoethyl phosphoramidite is an amine-protected nucleoside building block that has been used in the synthesis of oligonucleotides.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kungurtsev, V., Laakkonen, J., Molina, A.G., et al. Solution-phase synthesis of short oligo-2-deoxyribonucleotides by using clustered nucleosides as a soluble support. Eur. J. Org. Chem. 29, 6687-6693 (2013).