A nucleoside building block
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3’-dC(Bz)-2’-phosphoramidite

Item No. 43357

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-3′-deoxy-cytidine
CAS Number
157327-96-3
Molecular Formula
C46H52N5O8P
Formula Weight
833.9
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Sparingly soluble: 1-10 mg/ml
SMILES
O=C(NC(C=CN1[C@@H]([C@H](OP(N(C(C)C)C(C)C)OCCC#N)C2)O[C@@H]2COC(C(C=C3)=CC=C3OC)(C(C=C4)=CC=C4OC)C5=CC=CC=C5)=NC1=O)C6=CC=CC=C6
InChi Code
InChI=1S/C46H52N5O8P/c1-32(2)51(33(3)4)60(57-29-13-27-47)59-41-30-40(58-44(41)50-28-26-42(49-45(50)53)48-43(52)34-14-9-7-10-15-34)31-56-46(35-16-11-8-12-17-35,36-18-22-38(54-5)23-19-36)37-20-24-39(55-6)25-21-37/h7-12,14-26,28,32-33,40-41,44H,13,29-31H2,1-6H3,(H,48,49,52,53)/t40-,41+,44+,60?/m0/s1
InChi Key
QRUYOSQSJHNNHF-UOMJVJLHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $43

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    10 mg

    $73

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    25 mg

    $172

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    50 mg

    $280

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    Product Description

    3’-dC(Bz)-2’-phosphoramidite is a nucleoside building block that has been used in the synthesis of nuclease-resistant oligonucleotides.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Erande, N., Gunjal, A.D., Fernandes, M., et al. Synthesis and structural studies of S-type/N-type-locked/frozen nucleoside analogues and their incorporation in RNA-selective, nuclease resistant 2'-5' linked oligonucleotides. Org. Biomol. Chem. 11(5), 746-757 (2013).