A Certified Reference Material
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
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Research Tool(s)
15314(−)-Cotinine
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(−)-Cotinine (CRM)

A 1 mg/ml solution in methanol

Item No. 40379

Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • (S)-Cotinine
Technical Information
Formal Name
1-methyl-5S-(3-pyridinyl)-2-pyrrolidinone
CAS Number
486-56-6
Molecular Formula
C10H12N2O
Formula Weight
176.2
Formulation
A 1 mg/ml solution in methanol
SMILES
O=C1CC[C@@H](C2=CN=CC=C2)N1C
InChi Code
InChI=1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/t9-/m0/s1
InChi Key
UIKROCXWUNQSPJ-VIFPVBQESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $28

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    Product Description

    (−)-Cotinine (CRM) (Item No. 40379) is a certified reference material categorized as an alkaloid.1 (−)-Cotinine is an active metabolite of (−)-nicotine. It induces self-administration in rats.2 This product is intended for research and forensic applications. This product is also available as a general research tool (Item No. 15314).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. von Weymarn, L.B., Retzlaff, C., and Murphy, S.E. CYP2A6- and CYP2A13-catalyzed metabolism of the nicotine Δ5'(1')iminium ion. J. Pharmacol. Exp. Ther. 343(2), 307-315 (2012).

    2. Ding, Z.-M., Gao, Y., Sentir, A.M., et al. Self-administration of cotinine in wistar rats: Comparisons to nicotine. J. Pharmacol. Exp. Ther. 376(3), 338-347 (2021).