A sterol lipid and derivative of 5-androstenetriol
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Product Categories

Product Type

Biochemicals
Lipids
Sterol Lipids

Research Area

Cancer
Cell Death

(3β,4β,17β)-17-(2-Pyridinylmethyl)androst-5-ene-3,4,17-triol

Item No. 40438

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
17-(2-pyridinylmethyl)-androst-5-ene-3β,4β,17β-triol
CAS Number
1393651-00-7
Molecular Formula
C25H35NO3
Formula Weight
397.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlEthanol: Soluble: ≥10 mg/mlPBS (pH 7.2): Slightly soluble: 0.1-1 mg/ml
SMILES
C[C@@]12C3C(CC=C1[C@@H](O)[C@H](CC2)O)C4[C@](CC3)([C@](O)(CC5=NC=CC=C5)CC4)C
InChi Code
InChI=1S/C25H35NO3/c1-23-11-10-21(27)22(28)20(23)7-6-17-18(23)8-12-24(2)19(17)9-13-25(24,29)15-16-5-3-4-14-26-16/h3-5,7,14,17-19,21-22,27-29H,6,8-13,15H2,1-2H3/t17?,18?,19?,21-,22+,23+,24-,25+/m0/s1
InChi Key
VOJCRCXJCNNVLD-RZVICWFMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 µg

    $36

    Add

    1 mg

    $64

    Add

    5 mg

    $282

    Add
    Cayman Chemical
    Visit Our Cancer Resource Center
    Find Tools & Resources to Study the Hallmarks of Cancer
    • Cancer cell signaling & regulation
    • Cancer metabolism
    • Tumor microenvironment
    EXPLORE NOW
    Product Description

    (3β,4β,17β)-17-(2-Pyridinylmethyl)androst-5-ene-3,4,17-triol is a sterol lipid and derivative of 5-androstenetriol (Item No. 35273).1 It is cytotoxic to MDA-MB-231 breast, PC3 prostate, HeLa cervical, and HT-29 colon cancer cells (IC50s = 9, 52.1, 26.6, and 8 µM, respectively) but not MRC-5 fibroblasts (IC50 = >100 µM).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Djurendić, E.A., Ajduković, J.J., Sakač, M.N., et al. Synthesis and cytotoxic activity of some 17-picolyl and 17-picolinylidene androstane derivatives. Eur. J. Med. Chem. 54, 784-792 (2012).