A bile acid conjugate and an EPHA2 inhibitor
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N-Lithocholyl-L-Alanine

Item No. 40929

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(3α,5β)-3-hydroxy-24-oxocholan-24-yl]-L-alanine
CAS Number
1428095-28-6
Synonyms
  • Alanolithocholic Acid
Molecular Formula
C27H45NO4
Formula Weight
447.7
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly soluble: 0.1-1 mg/mlEthanol: Slightly soluble: 0.1-1 mg/ml
SMILES
C[C@H](CCC(N[C@@H](C)C(O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
InChi Code
InChI=1S/C27H45NO4/c1-16(5-10-24(30)28-17(2)25(31)32)21-8-9-22-20-7-6-18-15-19(29)11-13-26(18,3)23(20)12-14-27(21,22)4/h16-23,29H,5-15H2,1-4H3,(H,28,30)(H,31,32)/t16-,17+,18-,19-,20+,21-,22+,23+,26+,27-/m1/s1
InChi Key
QHTTURBEVRCUOI-JFCMIJDJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 mg

    $109

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    Product Description

    N-Lithocholyl-L-alanine is a bile acid conjugate and an ephrin type-A receptor 2 (EPHA2) inhibitor (IC50 = 19.95 µM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Incerti, M., Tognolini, M., Russo, S., et al. Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor. J. Med. Chem. 56(7), 2936-2947 (2013).