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Cytosine-13C,15N2 is intended for use as an internal standard for the quantification of cytosine (Item No. 36219) by GC- or LC-MS. Cytosine is a pyrimidine base.1 It forms complementary base pairs with the purine guanine (Item No. 34248) in DNA and RNA and is a precursor of uracil (Item No. 26088). Methylation of cytosine is a key epigenetic mark that plays a role in gene regulation.2
WARNING This product is not for human or veterinary use.
1. Nucleotide biosynthesis. Biochemistry (2002).
2. Epigenetic regulatory functions of DNA modifications: 5-